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Inhibition of the development of collagen-induced arthritis in rhesus monkeys by a small molecular weight antagonist of CCR5

✍ Scribed by Michel P. M. Vierboom; Paul J. Zavodny; Chuan-Chu Chou; Jayaram R. Tagat; Catherine Pugliese-Sivo; Julie Strizki; Ruo W. Steensma; Stuart W. McCombie; Liesbeth Çelebi-Paul; Ed Remarque; Margreet Jonker; Satwant K. Narula; Bert't Hart


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
230 KB
Volume
52
Category
Article
ISSN
0004-3591

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Prevention of murine collagen-induced ar
✍ Andrew C. Bakker; Leo A. B. Joosten; Onno J. Arntz; Monique M. A. Helsen; Alison 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 925 KB

Objective. To determine the efficacy of local human interleukin-1 receptor antagonist (HuIL-1Ra) gene therapy in murine collagen-induced arthritis (CIA). Methods. DBN1 mice were immunized against bovine type I1 collagen. Before the onset of arthritis, NIH/3T3 fibroblasts transfected with pMFG-IRAP