Chronic hepatitis C virus (HCV) infection is usually asymptomatic in children, but significant liver disease may occur. We evaluated the efficacy, safety, and pharmacokinetics of interferon alfa-2b and ribavirin in children with chronic HCV. We determined the optimal ribavirin dose in an initial coh
Inhibition of the cyclooxygenase/lipoxygenase pathways to improve interferon alfa efficacy in chronic hepatitis C: A wrong track
β Scribed by Anne Bastie; Laurent Castera; Francoise Roudot-Thoraval; Daniel Dhumeaux; Jean-Michel Pawlotsky
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 55 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0270-9139
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The aim of this study was to compare the short-term and long-term efficacy and safety of lymphoblastoid interferon with a recombinant interferon alfa (IFN-β£) in a 24-week treatment course for chronic hepatitis C. One thousand seventy-one patients with chronic hepatitis C were randomized to receive l
Combination treatment with pegylated-interferon-alpha (PEG IFN-β£) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may