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Inhibition of the constitutive activity of human 5-HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635

✍ Scribed by Adrian Newman-Tancredi; Caroline Conte; Christine Chaput; Michael Spedding; Mark J Millan


Book ID
110002822
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
275 KB
Volume
120
Category
Article
ISSN
0007-1188

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This study examined the influence of the highly selective 5-HT 1A receptor ligands, flesinoxan, S 15535, and WAY 100,635, upon the electrical activity of dopaminergic neurons in the ventral tegmental area (VTA), as compared to serotonergic neurons in the dorsal raphe nucleus (DRN) of anesthetized ra