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Inhibition of T-type Calcium Current in the Reticular Thalamic Nucleus by a Novel Neuroactive Steroid

✍ Scribed by PAVLE M. JOKSOVIC; DOUGLAS F. COVEY; SLOBODAN M. TODOROVIC


Book ID
111483616
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
189 KB
Volume
1122
Category
Article
ISSN
0890-6564

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In urethane-anesthetized rats a 0.36-mm metallic cannula for infusion was positioned in the somatosensory component of the thalamic reticular nucleus (sTR), where movement of the vibrissae evoked neuronal discharge. Infusion there of 0.125-0.5 microliter of a 50 mM solution of glutamate over a 1-min