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Inhibition of T-type Ca2+ currents in mouse spermatogenic cells by gossypol, an antifertility compound

✍ Scribed by Junping Bai; Yuliang Shi

Book ID
114014604
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
168 KB
Volume
440
Category
Article
ISSN
0014-2999

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The direct electrophysiological characterization of sperm Ca 2ϩ channels has been precluded by their small size and flat shape. An alternative to study these channels is to use spermatogenic cells, the progenitors of sperm, which are larger and easier to patch-clamp. In mouse and rat, the only volta