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Inhibition of synthesis of φX174 DNA in a mutant host thermosensitive for DNA synthesis

✍ Scribed by Steinberg, R.A.; Denhardt, D.T.


Book ID
122543333
Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
290 KB
Volume
37
Category
Article
ISSN
0022-2836

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Thermosensitive mutants of E. coli defective in DNA replication were tested for their capacity to support multiplication of phiA and phiX174. At the restrictive temperature, the viral growth was markedly affected in dnaH, dnaZ, or ligts7 mutants. Even when these strains were transfected with RF1 mol