Docosahexaenoic acid inhibits synaptic t
Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus
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Chainllie Young; Po-Wu Gean; Lih-Chu Chiou; Yu-Zen Shen
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Article
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2000
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John Wiley and Sons
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English
β 103 KB
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Docosahexaenoic acid (DHA) has been suggested to be required for neuronal development and synaptic plasticity. However, in view of the fact that DHA facilitates NMDA responses and blocks K(+) channels, it might predispose the neurons to epileptiform bursting. By using extracellular recording of popu