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Inhibition of suicidal erythrocyte death by nitric oxide

✍ Scribed by Jan P. Nicolay; Gerd Liebig; Olivier M. Niemoeller; Saisudha Koka; Mehrdad Ghashghaeinia; Thomas Wieder; Judith Haendeler; Rudi Busse; Florian Lang

Publisher
Springer
Year
2007
Tongue
English
Weight
471 KB
Volume
456
Category
Article
ISSN
0031-6768

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Evidence shows that Na(+)/K(+)-ATPase from kidney, brain and liver is inhibited by nitric oxide (NO) and peroxynitrite anion (ONO(2) (-)), but the mechanism is unknown. The aim of the present work was to study the inhibitory effect of NO and ONO(2) (-) on erythrocyte Na(+)/K(+)-ATPase. Erythrocyte m