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Inhibition of stimulated bone resorption in vitro by TIMP-1 and TIMP-2

โœ Scribed by Peter A Hill; John J Reynolds; Murray C Meikle


Book ID
119121806
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
337 KB
Volume
1177
Category
Article
ISSN
0167-4889

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## Abstract Matrix metalloproteinases (MMPs) are proteolytic enzymes that play critical roles in the pathogenesis of human cancers. Clinical trials using synthetic small molecule MMP inhibitors have been carried out but with little success. Tissue inhibitors of metalloproteinases (TIMPs) are endoge