๐”– Bobbio Scriptorium
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INHIBITION OF SICKLING BY DL-GLYCERALDEHYDE

โœ Scribed by Lehmann, H.; Kynoch, P.A.M.


Book ID
122654813
Publisher
The Lancet
Year
1972
Tongue
English
Weight
163 KB
Volume
299
Category
Article
ISSN
0140-6736

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Glyceraldehyde reacts with hemoglobin S in the intact erythrocyte to reduce the degree of polymerization, thereby inhibiting sickling of the erythrocyte. Only five of the 24 amino groups per C@ dimer react with glyceraldehyde; the adducts are present as ketoamine structures, formed by Amadori rearra