RNAse A-like enzymes in serum inhibit th
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Jörg Haupenthal; Christina Baehr; Stefan Zeuzem; Albrecht Piiper
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Article
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2007
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John Wiley and Sons
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French
⚖ 262 KB
## Abstract Down‐modulation of target molecules in tumor cells by small interfering (si) RNAs is a promising anti‐cancer strategy. A major challenge of this approach is the loss of silencing activity of the siRNAs __in vivo__. Our study aimed at investigating the influence of the serum compartment