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Inhibition of RNA polymerase as a possible anti-leukaemic action of cytosine arabinoside

✍ Scribed by CHUANG, RONALD Y.; CHUANG, LINDA F.


Book ID
109698853
Publisher
Nature Publishing Group
Year
1976
Tongue
English
Weight
240 KB
Volume
260
Category
Article
ISSN
0028-0836

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Action of cytosine arabinoside on human
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## Abstract Tumor cells were isolated from malignant effusions of three patients with disseminated solid tumors of different origin. Intracellular accumulation of nondiffusible cytosine arabinoside (ara‐C) nucleotides was used to measure phosphorylation. Mouse leukemia L 1210 and L 1210/CA, and ara