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Inhibition of Rho-kinase induces αB-crystallin expression in lens epithelial cells

✍ Scribed by Rahul N Khurana; Rupa Latha Maddala; Hiroaki Shimokawa; J Samuel Zigler; David L Epstein; P Vasantha Rao

Book ID
117052056
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
234 KB
Volume
294
Category
Article
ISSN
0006-291X

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Previous transfection experiments have shown that 162 base pairs (bp) of the 5' flanking sequence of the chicken alpha A-crystallin gene are required for promoter activity in primary chicken lens epithelial cells (PLE), while only 111 bp of the 5' flanking sequence are needed for activity of the mou