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Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon

✍ Scribed by J. Allen Crow; Victoria Bittles; Katye L. Herring; Abdolsamad Borazjani; Philip M. Potter; Matthew K. Ross


Book ID
113924949
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
225 KB
Volume
258
Category
Article
ISSN
0041-008X

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## Abstract Parathion (PS) and chlorpyrifos (CPF) are organophosphorus insecticides, which elicit toxicity following biotransformation to the potent acetylcholinesterase inhibitors, paraoxon (PO) and chlorpyrifos oxon (CPO). Both oxons have also been shown to interact directly with muscarinic recep