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Inhibition of rat platelet aggregation by a Prudhoe Bay crude oil and its aliphatic, aromatic, and heterocyclic fractions

โœ Scribed by Shibani Chaudhury; Stephen Macko; A.D. Rahimtula


Book ID
113207063
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
881 KB
Volume
90
Category
Article
ISSN
0041-008X

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Administration of a Prudhoe Bay crude oil (PBCO) to rats has been shown to (a) inhibit platelet aggregation induced by adenosine diphosphate (ADP), arachidonic acid, or epinephrine and (b) induce benzo-a-pyrene hydroxylase (BPH) in the liver and small intestine. Maximum inhibition of aggregation (90