Inhibition of Rat and Human Cytochrome P4502E1 Catalytic Activity and Reactive Oxygen Radical Formation by Nitric Oxide

Caspase-independent cell death by low co

Caspase-independent cell death by low concentrations of nitric oxide in PC12 cells: Involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria

✍ Kohei Yuyama; Hideko Yamamoto; Itone Nishizaki; Takeshi Kato; Ichiro Sora; Toshi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 689 KB

## Abstract We reported previously that low levels of nitric oxide (NO) induced cell death with properties of apoptosis, including chromatin fragmentation and condensation in undifferentiated PC12 pheochromocytoma cells. The present study demonstrates that cytotoxicity of low concentrations of NO i