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Inhibition of pyrimidine metabolism in myeloid leukemia cells by triazole and pyrazole nucleosides

✍ Scribed by Steven S. Matsumoto; James M. Fujihaki; L.Dee Nord; Randall C. Willis; Vincent M. Lee; Brahma S. Sharma; Yogesh S. Sanghvi; Ganesh D. Kini; Ganapathi R. Revankar; Roland K. Robins; Weldon B. Jolley; Roberts A. Smith

Book ID
115781352
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
861 KB
Volume
39
Category
Article
ISSN
0006-2952

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## Abstract It is shown that a 5‐day schedule of two injections per day of the myeloid differentiation‐inducing protein MGI‐2 inhibited the __in vivo__ development of leukemia in SL and SJL/J mice with different syngeneic MGI^+^D^+^ clones of myeloid leukemic cells. With this schedule of treatment