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Inhibition of protein synthesis induced by adenine nucleotides requires their metabolism into adenosine

✍ Scribed by Sandrine Tinton; Pedro Buc-Calderon

Book ID
115784300
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
897 KB
Volume
50
Category
Article
ISSN
0006-2952

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P1,P5-di(adenosine 5')pentaphosphate (Ap5A) is an excellent inhibitor of human hemolysate adenylate kinase at concentrations near 2 microM and above. At ten times this concentration and in hemolysate enzyme assays under conditions described in this paper it appears not to alter reaction data in the