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Inhibition of protein synthesis antagonizes induction of sister-chromatid exchanges by exogenous agents

✍ Scribed by Akira Sono; Kengo Sakaguchi

Book ID
113192119
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
603 KB
Volume
80
Category
Article
ISSN
0027-5107

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Induction of sister chromatid exchanges
Induction of sister chromatid exchanges by inhibitors of topoisomerases
✍ Meesun Lim; Leroy F. Liu; David Jacobson-Kram; Jerry R. Williams πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 565 KB

To investigate the role of topoisomerases in the production of sister chromatid exchanges, the effects of inhibitors of type I and H topoisomerases on baseline and mutagen-induced sister chromatid exchanges were compared. V79 cells were treated with VM-26 and m-AMSA, known inhibitors of type H topoi