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Inhibition of protein kinases by bis-ATP mimics

✍ Scribed by M Houdin; C Sergheraert


Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
517 KB
Volume
27
Category
Article
ISSN
0223-5234

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Several tyrosine and serine/threonine protein kinases have emerged in the last few years as attractive targets in the search for new therapeutic agents being applicable in many different disease indications. Initially, inhibition of these protein kinases by ATP site-directed inhibitors was considere