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Inhibition of proliferation of cultured cells by polyamine and cysteine interaction

✍ Scribed by Dewey, D.L.; Gaugas, J.M.


Book ID
122499852
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
378 KB
Volume
10
Category
Article
ISSN
0304-3835

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We investigated the effects of an irreversible inhibitor of ornithine decarboxylase, difluoromethylornithine (DFMO), on the proliferation, polyamine content, and plating efficiency of five human adenocarcinoma cell lines in vitro. DFMO inhibited the growth of all five lines when added at concentrati