We have reported differential expression of 70-kDa heat shock protein (HSP70) in human oral tumorigenesis. The functional significance of elevated levels of HSP70 protein in oral squamous cell carcinomas (SCC) remains to be elucidated. The present study was designed to investigate the role of HSP70
β¦ LIBER β¦
Inhibition of proliferation and induction of apoptosis by abrogation of heat-shock protein (HSP) 70 expression in tumor cells
β Scribed by Yu-quan Wei; Xia Zhao; Yoshitaka Kariya; Keisuke Teshigawara; Atsushi Uchida
- Publisher
- Springer-Verlag
- Year
- 1995
- Tongue
- English
- Weight
- 730 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0340-7004
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Objective: The 70kD heat shock protein (Hsp70), induced when cells are subjected to environmental stress, prevents the denaturation and incorrect folding of polypeptides and may expedite replication and transmission of DNA and RNA viruses. We analyzed whether messenger RNA (mRNA) for Hsp70 was expre