Inhibition of polyethylene glycol–induced histamine release by monomeric ethylene and diethylene glycol: A case of probable polyethylene glycol allergy

Inhibition of cytarabine-induced MDR1 (P

Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function

✍ Pavel G. Komarov; Alexander A. Shtil; Lela E. Buckingham; M. Balasubramanian; Ol 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 734 KB

Fatty acid ester surfactants Cremophor EL and Solutol H S I 5 were described earlier as modulators of multidrug resistance mediated by MDR I P-glycoprotein (Pgp). We have shown that the most active components of these polydisperse surfactants are fatty acid-polyethylene glycol-fatty acid diesters (F