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Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3′-pyridinylmethyl)benzofuran-2-carboxylate

✍ Scribed by R.R. Gorman; R.A. Johnson; C.H. Spilman; J.W. Aiken


Book ID
119049538
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
855 KB
Volume
26
Category
Article
ISSN
0090-6980

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The effects of CGS 13080, a thromboxane (TXA2) synthase inhibitor, on airway responses to arachidonic acid (AA) were investigated in the anesthetized cat. Feline and human lung microsomal fraction exhibited prostaglandin I2 (PGI2, prostacyclin), and TXA2 synthase activities, and human platelet micro