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Inhibition of placental P-glycoprotein: impact on indinavir transfer to the foetus

✍ Scribed by Sreeja Sudhakaran; Craig R. Rayner; Jian Li; David C. M. Kong; Neil M. Gude; Roger L. Nation


Book ID
118700009
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
557 KB
Volume
65
Category
Article
ISSN
0306-5251

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In Vitro absorption and secretory quotie
✍ Victoria E. Thiel-Demby; Timothy K. Tippin; Joan E. Humphreys; Cosette J. Serabj πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 92 KB πŸ‘ 1 views

The absorptive (AQ) and secretory (SQ) quotients have been proposed as a novel experimental approach to quantify the modulation of intestinal absorption and secretion by P-glycoprotein (Pgp). Because these unidirectional assays inherently assess for the impact of Pgp, conclusions as to whether a com