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Inhibition of pig liver esterase by trifluoromethyl ketones: modulators of the catalytic reaction alter inhibition kinetics

โœ Scribed by Allen, Karen N.; Abeles, Robert H.


Book ID
127387492
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
777 KB
Volume
28
Category
Article
ISSN
0006-2960

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An Isothermal Titration Calorimetric Met
โœ Lifeng Cai; Aoneng Cao; Luhua Lai ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 68 KB

An isothermal titration calorimetric (ITC) method was developed to measure the kinetic parameters of ribonuclease A catalytic hydrolysis of cytidine 2',3'-cyclic monophosphate. Employing the inhibition of product as a probe, the K(m), K(i), k(c), and DeltaH(m) can be determined by two simple calorim