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Inhibition of phospholipase A2 modulates glycogen synthase kinase (GSK) activity and Tau phosphorylation in primary cultures of cortical and hippocampal neurons

✍ Scribed by Vanessa J.R. de Paula; Leda L. Talib; Wagner F. Gattaz; Orestes V. Forlenza


Book ID
118465146
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
68 KB
Volume
5
Category
Article
ISSN
1552-5260

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## Interleukin-1 beta (IL-1␀ ) is an inflammatory cytokine whose expression is elevated in brain during seizures, ischemia, and injury. Expression of IL-1␀ and its receptor can also be observed in normal brain. Platelet-activating factor (PAF) is also a dual mediator that promotes neuronal plastici