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Inhibition of phosphodiestrase 9 induces cGMP accumulation and apoptosis in human breast cancer cell lines, MCF-7 and MDA-MB-468

✍ Scribed by R. Saravani; F. Karami-Tehrani; M. Hashemi; M. Aghaei; R. Edalat


Book ID
118700141
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
719 KB
Volume
45
Category
Article
ISSN
0960-7722

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✍ Kate M. Suchanek; Fiona J. May; Jodie A. Robinson; Won Jae Lee; Nicola A. Holman 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB

## Abstract Peroxisome proliferator–activated receptor (PPAR) α is a ligand‐activated transcription factor that has been linked with rodent hepatocarcinogenesis. It has been suggested that __PPARα__ mRNA expression levels are an important determinant of rodent hepatic tumorigenicity. Previous work