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Inhibition of PhIP mutagenicity by catechins, and by theaflavins and gallate esters

✍ Scribed by Zenon Apostolides; Douglas A Balentine; Matthew E Harbowy; Yukihiko Hara; John H Weisburger


Book ID
117767397
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
171 KB
Volume
389
Category
Article
ISSN
1383-5718

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## Abstract Chemical model investigation showed that both epigallocatechin gallate (EGCG) and its peracetate, which has all the hydroxyl groups acetylated, effectively reduced the formation of 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__]pyridine (PhIP), the most abundant mutagenic heterocyclic amine