Inhibition of patulin production by Penicillium expansum cultured with neem (Azadirachta indica) leaf extracts

✍ Scribed by Simone Aparecida Galerani Mossini; Kesia Pires De Oliveira; Carlos Kemmelmeier

• Book ID: 102388720
• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 222 KB
• Volume: 44
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/jobm.200310332

✦ Synopsis

Abstract

Aqueous extract of the leaves of neem [Azadirachta indica A. Juss (Meliaceae)] was tested in vitro for antifungal activity against Penicillium expansum. Patulin production was inhibited during cultivation, when concentrations higher than 50 mg/ml of neem leaf extract was added to the culture medium. Analyses of mycotoxin production were performed by TLCAbbreviations used: TLC, Thin layer chromatography; HPLC, High‐performance liquid chromatography; UEM, Universidade Estadual de Maringá [State University of Maringá]; IAPAR, Instituto Agrônomico do Paraná [Agronomy Institute of Paraná].

and HPLC. Fungal growth and colony characteristics, in the presence of the extract, were investigated and compared with extract‐free cultures. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)