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Inhibition of PARP-1 attenuates tau phosphorylation by regulation of glycogen synthase kinase-3

โœ Scribed by Author affiliation TBD


Book ID
118467281
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
163 KB
Volume
7
Category
Article
ISSN
1552-5260

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## Abstract Tauopathies, including Alzheimer's disease (AD), are a group of neurodegenerative disorders characterized by the presence of intraneuronal filamentous inclusions of abnormally phosphorylated tau protein. In AD brains, it has been shown that the level of abnormally phosphorylated tau is