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Inhibition of p53-p21 pathway promotes the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes

✍ Scribed by XueBo Yan; AnLin Lv; YuJie Xing; BoWu Liu; Jing Hou; Wei Huang; Yao Li


Book ID
106459517
Publisher
Springer
Year
2011
Tongue
English
Weight
680 KB
Volume
354
Category
Article
ISSN
0300-8177

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## Abstract Differentiation of stem cells is tightly regulated by the microenvironment which is mainly composed of nonparenchymal cells. Herein, we investigated effect of hepatic stellate cells (HSCs) in different states on mesenchymal stem cells (MSCs) differentiation. Rat HSCs were isolated and s