Roles of p300, pocket proteins, and hTBP
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Nianli Sang; Maria Laura Avantaggiati; Antonio Giordano
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Article
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1997
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John Wiley and Sons
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English
โ 99 KB
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The conserved region 1 and the extreme N-terminus of adenoviral oncoprotein E1A are essential for transforming activity. They also play roles in the interaction of E1A with p300/CBP and pRb and are involved in both transactivation and repression of host gene expression. It was reported recently that