𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of p38 MAP kinase as a target for prophylaxis of postoperative ileus

✍ Scribed by Sven Wehner; Stefan Straesser; Mariola Lysson; Andreas Hirner; Joerg C. Kalff


Book ID
113678572
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
50 KB
Volume
207
Category
Article
ISSN
1072-7515

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Identification of Op18/stathmin as a pot
✍ Kenji Mizumura; Kohsuke Takeda; Shu Hashimoto; Takashi Horie; Hidenori Ichijo 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 312 KB

## Abstract Apoptosis signal‐regulating kinase 1 (ASK1) is a mitogen‐activated protein (MAP) kinase kinase kinase that activates the JNK and p38 MAP kinase cascades and has a broad range of biological activities including cell differentiation and stress‐induced apoptosis. However, effector molecule

Substituted Isoxazoles as Potent Inhibit
✍ Stefan A. Laufer; Simona Margutti; Martina D. Fritz 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB 👁 2 views

## Abstract __In a continuous effort to develop improved p38 MAP (mitogen‐activated protein) kinase inhibitors, we focused our attention on the suitability of the isoxazole ring as a bioisosteric replacement for the imidazole ring of SB‐203580. 3,4‐ and 4,5‐disubstituted as well as 3,4,5‐trisubstit