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Inhibition of oral contraceptive steroid-metabolizing enzymes by steroids and drugs

✍ Scribed by FP Guengerich

Book ID
118890658
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
129 KB
Volume
36
Category
Article
ISSN
0020-7292

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✍ Rashmi V. Patwardhan; Mack C. Mitchell; Raymond F. Johnson; Steven Schenker πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 610 KB

The effects of oral contraceptive steroids (OCS) on the disposition and elimination of lorazepam, oxazepam, and chlordiazepoxide were examined. Lorazepam and oxazepam are metabolized via glucuronidation while chlordiazepoxide is metabolized by oxidation in the liver. The disposition and elimination