Inhibition of nuclear T3 binding by fatt
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Wilmar M. Wiersinga; Inder J. Chopra; Guadalupe N. Chua Teco
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Article
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1988
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Elsevier Science
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English
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Studies were performed to evaluate a possible modulatory role of lipids on the binding of T, to rat liver nuclear receptors in vitro. Unsaturated fatty acids were potent inhibitors of the binding of ['261] T, to isolated rat liver nuclei. Doses (in pmol/L) causing a 50% inhibition of nuclear T, bind