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Inhibition of Nuclear Factor-κB Enhances the Antitumor Effect of Paclitaxel Against Gastric Cancer with Peritoneal Dissemination in Mice

✍ Scribed by Koichiro Haruki, Hiroaki Shiba, Yuki Fujiwara, Kenei Furukawa, Ryota Iwase, Tadashi Uwagawa, Takeyuki Misawa, Toya Ohashi, Katsuhiko Yanaga

Book ID: 118298884
Publisher: Springer US
Year: 2012
Tongue: English
Weight: 918 KB
Volume: 58
Category: Article
ISSN: 0163-2116
DOI: 10.1007/s10620-012-2311-4

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## Abstract Activation of nuclear factor‐kappa B (NF‐κB) has been detected in various malignant tumors, including gastric carcinoma, and is associated with tumor growth, metastasis, resistance to chemotherapeutic agents and poor prognosis. Therefore, NF‐κB is a potential target for antitumor therap