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Inhibition of noradrenaline release by antibodies to B-50 (GAP-43)

โœ Scribed by Dekker, L. V.; Graan, P. N. E. De; Oestreicher, A. B.; Versteeg, D. H. G.; Gispen, W. H.


Book ID
109761622
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
388 KB
Volume
342
Category
Article
ISSN
0028-0836

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Antibodies directed to the calmodulin-bi
โœ Jacques J.H. Hens; Govert Hoogland; Pim J. French; Frans Boomsma; Pierre N. E. D ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 658 KB

is an atypical calmodulin-binding protein with a higher affinity for calmodulin in the absence than in the presence of Ca2+. In the mature synapse B-50 has been implicated in the release of noradrenaline and neuropeptide cholecystokinin-8. Using the cross-linker disuccinimidyl suberate we demonstrat