In recent years, NO, a gas previously considered a potentially toxic chemical, has become established as a diffusible universal messenger mediating cell-cell communication throughout the body. In mammals, NO is a recognized mediator of blood vessel relaxation that helps to maintain blood pressure. I
✦ LIBER ✦
Inhibition of nitric oxide synthase — potential for a novel class of therapeutic agent?
✍ Scribed by Jill E. Ogden; Philip K. Moore
- Book ID
- 114151985
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 1020 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0167-7799
No coin nor oath required. For personal study only.
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## Abstract Inhibitors of the family of nitric oxide synthases (NOS‐I–III; EC 1.14.13.39) are of interest as pharmacological agents to modulate pathologically high nitric oxide (NO) levels in inflammation, sepsis, and stroke. In this article, we discuss the approach for targeting the unique (__6R__