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Inhibition of nitric oxide release by an aqueous extract of Tinospora tuberculata

โœ Scribed by Dr Takako Yokozawa; Tian Shan Wang; Cui Ping Chen; Masao Hattori

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
46 KB
Volume
14
Category
Article
ISSN
0951-418X

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โœฆ Synopsis

An aqueous extract of Tinospora tuberculata stems was found to scavenge nitric oxide (NO) in vitro in both cell and cell-free systems. When the aqueous extract was added to lipopolysaccharide-stimulated murine macrophages, it inhibited NO release dose-dependently, and similar activity was found in a cell-free system using sodium nitroprusside as a NO donor. These findings may help to explain, in part, certain pharmacological activities of Tinospora tuberculata.

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