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Inhibition of nicotine-induced hyperactivity by 5-HT3 receptor antagonists

✍ Scribed by P.C. Moser

Book ID
115884139
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
110 KB
Volume
183
Category
Article
ISSN
0014-2999

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The effect of two potent and specific antagonists of 5HT3 receptors, ICS 205-930 and MDL 72222, on the reinforcing properties of amphetamine, morphine and nicotine was studied in rats. Durg-induced reinforcement was assessed by measuring drug-conditioned place preference. ICS 205-930 and MDL 72222 d