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Inhibition of NF-KB Does Not Induce C-Jun N-Terminal Kinase-Mediated Apoptosis in Reperfusion Injury

✍ Scribed by Gregory D. Rushing; L.D. Britt


Book ID
113677681
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
430 KB
Volume
204
Category
Article
ISSN
1072-7515

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## Abstract To elucidate the possible effect of NFΞΊB on radioresistance, we used the osteosarcoma cell line Saos2, stably expressing the NFΞΊB constitutive inhibitor, mIΞΊB (Saos2‐mIΞΊB) or stably transfected with the empty vector (Saos2‐EV). Ionizing radiation induced β€œintrinsic” apoptosis in Saos2‐m