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Inhibition of neutrophil-mediated cytotoxicity by α2 macroglobulin

✍ Scribed by G. Cordier; J. P. Revillard

Book ID
105417128
Publisher
Springer
Year
1980
Tongue
English
Weight
663 KB
Volume
36
Category
Article
ISSN
1420-682X

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Peripheral blood monocyte-derived macrophages and polymorphonuclear leukocytes (PMNs) obtained from normal donors kill tumor cells in vitro. However, if verapamil is added to the macrophages or neutrophil tumor cell suspensions in microgram concentrations (0.1 pg to 0.1 mg), there is marked inhibiti