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Inhibition of neutrophil-dependent cytotoxicity for human endothelial cells by antirheumatic drugs

✍ Scribed by J. Bratt; J. Palmblad


Book ID
114053826
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
1016 KB
Volume
128
Category
Article
ISSN
1532-6543

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The mechanism of action of bucillamine, [N-(2-mercapto-2-methylpropionyl)-L-cysteine] (BC), a novel antirheumatic drug that is used in patients with rheumatoid arthritis (RA), was compared with that of D-penicillamine (DP). BC inhibited phytohemagglutinin (PHA)-induced DNA synthesis of peripheral bl