Melatonin and its brain metabolite N1-ac
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Víctor Tapias; Germaine Escames; Luis C. López; Ana López; Encarnación Camacho;
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Article
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2009
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John Wiley and Sons
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English
⚖ 181 KB
## Abstract Melatonin prevents mitochondrial failure in models of sepsis through its ability to inhibit the expression and activity of both cytosolic (iNOS) and mitochondrial (i‐mtNOS) inducible nitric oxide synthases. Because Parkinson's disease (PD), like sepsis, is associated with iNOS induction