Inhibition of Natural Killer Cell Cytotoxicity by Cell Growth-related Molecules
β Scribed by Tamura, Yasuaki ;Takashima, Satoru ;Cho, Joong-Moon ;Qi, Weimin ;Kamiguchi, Kenjiro ;Torigoe, Toshihiko ;Takahashi, Shuji ;Hirai, Itaru ;Sato, Noriyuki ;Kikuchi, Kokichi
- Book ID
- 108581218
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1996
- Tongue
- English
- Weight
- 479 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0910-5050
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## Abstract Natural killer (NK) cells are a class of lymphocytes important in immune resistance to viral and other serious diseases. The cytotoxic function, or βkilling activityβ of NK cells has become important in studies of the effects of stress and other psychosocial factors on physical health.
We have tried to identify carbohydrate structures involved in recognition and/or lysis of K562 target cells by human natural killer (NK) cells. Inhibition studies were performed with mono-, di-and trisaccharides, and with glycopeptides and glycoproteins of known carbohydrate composition. When tested