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Inhibition of Na+, K+-ATPase Activity by the Metabolites Accumulating in Homocystinuria

✍ Scribed by Emilio L. Streck; Alexandra I. Zugno; Bárbara Tagliari; Clovis M.D. Wannmacher; Moacir Wajner; Angela T.S. Wyse


Book ID
110338447
Publisher
Springer
Year
2002
Tongue
English
Weight
60 KB
Volume
17
Category
Article
ISSN
0885-7490

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The K +-induced hyperpolarization of Na-loaded mouse diaphragm muscle, enzymatic activity of Na,K-ATPase and 3H-ouabain binding to rat brain microsornes was measured in the presence of K+ channel blockers tetraethylammonium (TEA), tetrabutylammonium (TBA) and apamin. TBA, and to a lesser extent TEA