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Inhibition of myoblast differentiation by Sfrp1 and Sfrp2

✍ Scribed by Simon Descamps; Hayat Arzouk; Francis Bacou; Henri Bernardi; Yann Fedon; Stéphanie Gay; Yves Reyne; Bernadette Rossano; Jonathan Levin

Book ID
106139456
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
274 KB
Volume
332
Category
Article
ISSN
0302-766X

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## Abstract Osteoblasts and adipocytes are thought to derive from a common bone marrow stromal cell (BMSC) precursor. Activation of the canonical Wnt signaling pathway plays a pivotal role in the differentiation of BMSCs along either of these two lineages, promoting osteogenesis and inhibiting adip