Inhibition of multiplication of parainfluenza 3 virus in prostaglandin-treated WISH cells
β Scribed by M. Luczak; W. Gumulka; S. Szmigielski; M. Korbecki
- Publisher
- Springer Vienna
- Year
- 1975
- Tongue
- English
- Weight
- 299 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1432-8798
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## Abstract Addition of 5 to 250 micromolar adenosine to the culture medium resulted in a 30β80% inhibition of the rate of uptake of 2βdeoxyglucose or 3β0βmethylglucose by sparse or confluent 3T3 cells within three hours. The inhibition of deoxyglucose uptake could be reversed partially by changing
Prostaglandin (PG) D(2), and its metabolites, are known to be important mediators during acute and chronic inflammation. However, their functions during the early phases of the immune response are poorly documented. In the present study, we show that PGD(2 )inhibits, in a dose-dependent manner, the