Two years or more after 35 patients (29 men and six women) with chronic hepatitis B were treated by interferon, we studied relationships of age, ALT activity, activity of serum DNA polymerase associated with the hepatitis B virus, serum levels of hepatitis B e antigen and activity of 2',5'-oligoaden
Inhibition of Mouse Fibroblast Interferon by Gangliosides : Differential Effects on Biological Activity and on Induction of (2′-5′)Oligoadenylate Synthetase
✍ Scribed by Chitra KRISHNAMURTI; Françoise BESANÇON; Just JUSTESEN; Kenneth POULSEN; Helmut ANKEL
- Book ID
- 115120989
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 601 KB
- Volume
- 124
- Category
- Article
- ISSN
- 1432-1327
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Partially pure immune (gamma) interferon (IFN-gamma) was administered to patients intramuscularly (IM), by rapid IV bolus, and by 6-h continuous infusion as part of a phase I clinical trial. The activity of 2',5'-oligoadenylate synthetase (2,5 A) in peripheral blood cells and the concentration of be
## Abstract Human α interferon (IFN‐α) and β interferon (IFN‐β) showed antiviral and anticellular effects on human lymphoblastoid Daudi and P3HR‐1 cells, but up to 1,000 units/ ml of γ interferon (IFN‐γ) showed no such effect. Though a fairly high level of dsRNA‐dependent 2′‐5′‐oligoadenylate synth